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Open Access Highly Accessed Research article

Reporting of adverse drug reactions: an exploratory study among nurses in a teaching hospital, Ajman, United Arab Emirates

Lisha Jenny John1*, Mohamed Arifulla2, Jenny John Cheriathu3 and Jayadevan Sreedharan4

Author Affiliations

1 Lecturer, Department of Pharmacology, Gulf Medical University, Ajman, United Arab Emirates

2 Professor and Head, Department of Pharmacology, Gulf Medical University, Ajman, United Arab Emirates

3 Lecturer and Specialist, Department of Pediatrics, Gulf Medical College Hospital and Research Center, Ajman, United Arab Emirates

4 Professor and Assistant Director, Research Division, Gulf Medical University, Ajman, United Arab Emirates

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DARU Journal of Pharmaceutical Sciences 2012, 20:44  doi:10.1186/2008-2231-20-44

Published: 4 October 2012

Abstract

Background and the purpose of the study

Adverse drug reactions (ADRs) are important public health problem associated with morbidity, mortality and financial burden on the society. Nurses play important role in medication safety surveillance through the spontaneous voluntary reporting of ADRs. Nurses’ knowledge, attitude and practice towards ADR reporting and factors affecting reporting was assessed in the study.

Methods

All nurses working in a tertiary care hospital, Ajman, UAE participated in this cross-sectional survey. A self administered questionnaire of four domains (knowledge, attitude, practice, factors affecting reporting) was distributed among nurses after obtaining informed consent. The knowledge and attitude components were assigned score of one for correct response. Data was analyzed using SPSS (version 19). Mann–Whitney U test was used to compare knowledge and attitude scores between subgroups; Spearman’s correlation for any relationship between knowledge and attitude.

Results

Of the total participants, females constituted 92.3%; average duration of clinical experience 6.5 ± 3.3 years; mean age 28.9 ± 4.1 years. Median score for knowledge components of ADR reporting was 11(total score: 17) and for attitude components was 4(total score: 8). No difference noted in knowledge and attitude scores between gender, age group, educational qualification. A positive correlation between knowledge and attitude components was observed (r = 0.38). ADRs are important cause for morbidity and mortality was reported by (54.9%). 49.5% were aware of Pharmacovigilance centers’. Uncertainty of ADRs (49.5%); concern that the report may be wrong (46.2%) and inadequate knowledge of ADR reporting procedure were the major barriers to reporting. Training in ADR reporting as the key measure to improve reporting was suggested by (86.8%).

Major conclusion

The results of the study strongly point out the need for interventional program among nurses focusing on the importance of ADR reporting and reporting procedure to encourage their active, voluntary participation in drug safety surveillance.